There are weird things going on in your basement laboratories. They keep asking for more barrels of quicksilver, or bits of your hair. Well it's all in progress. They're seeking for a way to turn lead into gold, or at least into something better than lead. That lead had just been too good of a deal to pass up; you didn't think, where do I put all this lead? What am I going to do with this lead? Well it will all be sorted out. They're also seeking for a universal solvent. If they can do that one, you will take whatever they use to hold it in and build a castle out of it. A castle that cannot be dissolved! Now that's something.
This adds new Kingdom cards to Dominion and as it is an expansion, it can't be played by itself, you will need Dominion, or Dominion: Intrigue to play the game.
Dominion: Alchemy may also be combined with any other Dominion expansions you have.