In Antidote, you are a scientist working for a giant chemical research conglomerate. When a deadly toxin suddenly infects you and everyone in your lab, you must work quickly to share your research and find the Antidote before it's too late.
In the game, players will take turns deciding what action all other players take: either discard from their hand or trade research with other players. Eventually all your cards run-out and you will be left with just one that you must "drink" and hope it's the Antidote. If this card is the real Antidote, you're cured and live to play again! If not... you die, but you can try again!
Antidote has 6 core elements:
Deduction: Players "live" or "die" by figuring out the one card type that has been removed from the game (similar to Clue).
Semi-Cooperative Gameplay: You live or die alone, but it might be impossible to deduce the Antidote without working with the other players.
Simultaneous action selection: Each turn involves every player. Whether it is trading for valuable information or simultaneously declassifying your research, all players are constantly engaged. This makes the game experience more fulfilling and removes long-periods of "down-time" between turns.t
Player-controlled game length: Players have full control over the pace of the game. If you believe you know the answer you can speed the game towards its conclusion. If not... don't hold your breath! No one is going to wait for you to work it out! This element gives a feeling of tension and excitement.
Multiple levels of player interaction: Even a simple "wink" or a "nod" can have meaning in this game if you are trying to learn or pass information between players. At the same time, a blatant statement such as "Blue formulas are toxic" might have no meaning at all, but everyone will judge you by your actions (everyone can see the cards you choose to discard).
Surprise ending: It is unlikely that anyone can know with 100% certainty what the Antidote is at the end of the game. This means the revealing of the Antidote is usually a surprise.